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Detroit Lions at Buffalo Bills odds

Detroit
Lions
SM rating 1592 · #9
31 – 41
Final
Bills -5.5 covered
Over 54.5
vs the most common closing line
Thursday, September 17
8:15 PM ET
Highmark Stadium
Buffalo
Bills
SM rating 1697 · #2
DET 34%BUF 66%
Fair moneyline
+197 / -197
DET / BUF, no vig
Market win %
32% / 68%
No-vig average of the books
Model vs market
DET +2 pts
SharpModels 34% · market 32% (no vig)
Ratings
1592 / 1697
DET / BUF, SharpModels

SharpModels is a benchmark built only from team ratings: it doesn't see injuries, rest or lineup news. When it and the market disagree, the market often knows something.

Closing lines

This game was played before we started collecting prices (22 October 2026), so we have its closing prices only, from DraftKings, FanDuel and bet365: no line movement or player props. A price can differ from the book's own by a cent or two.

MarketBest
Lions
Moneyline
+205
bet365
+195 +198 +205
Bills
Moneyline
-238
DraftKings
-238 -238 -250
Lions
Spread
+5.5-110
bet365
+5.5-116 +5.5-115 +5.5-110
Bills
Spread
-5.5-105
DraftKings
-5.5-105 -5.5-105 -5.5-110
Over
Total
54.5-115
FanDuel
- 54.5-115 55-112
Under
Total
55-108
bet365
- 54.5-105 55-108
Margin
Moneyline
3.1% 4.1%3.8%4.0%
MarketBest
Lions
Moneyline
+175
bet365
+160 +175
Bills
Moneyline
-192
DraftKings
-192 -208
Lions
Spread
+3.5-115
bet365
+3.5-116 +3.5-115
Bills
Spread
-3.5-105
bet365
-3.5-105 -3.5-105
Over
Total
27.5+100
bet365
- 27.5+100
Under
Total
27.5-120
bet365
- 27.5-120
Margin
Moneyline
2.1% 4.0%3.7%
MarketBest
Lions
Moneyline
+136
DraftKings
+136 +130
Bills
Moneyline
-154
bet365
-164 -154
Lions
Spread
+0.5-119
DraftKings
+0.5-119 +0.5-120
Bills
Spread
-0.5+100
bet365
-0.5-102 -0.5+100
Over
Total
10-120
bet365
- 10-120
Under
Total
10+100
bet365
- 10+100
Margin
Moneyline
2.9% 4.3%3.9%

Margin: how much a book builds into its moneyline (its implied chances add up to more than 100%). Lower is fairer; the lowest is in green. Under Best, the margin if you took the best price on each side.

Every price change, book by book: tap the table icon by any selection, line, team total or player.

Best spread and total weigh the line against the price: a better line is worth paying a little more for, most of all onto key numbers (getting off or onto 3 in the NFL is worth about 15-20 cents). Moneyline: simply the best price.

Alternate lines

BUF line
-5.5
DET +5.5
-105-116 -105-115 -110-110

Top number: BUF at that line; bottom: DET at the opposite line. Gold = best top number.

Total
40.5
Over / Under
- - -769+440
41
Over / Under
- - -769+425
41.5
Over / Under
- - -667+375
42
Over / Under
- - -625+370
42.5
Over / Under
- - -625+355
43
Over / Under
- - -588+348
43.5
Over / Under
- - -500+325
44
Over / Under
- - -455+314
44.5
Over / Under
- - -400+275
45
Over / Under
- - -385+270
45.5
Over / Under
- - -357+255
46
Over / Under
- - -345+250
46.5
Over / Under
- - -333+240
47
Over / Under
- - -312+230
47.5
Over / Under
- - -278+200
48
Over / Under
- - -270+195
48.5
Over / Under
- - -256+182
49
Over / Under
- - -250+180
49.5
Over / Under
- - -233+172
50
Over / Under
- - -213+166
50.5
Over / Under
- - -196+156
51
Over / Under
- - -182+146
51.5
Over / Under
- - -161+132
52
Over / Under
- - -159+128
52.5
Over / Under
- - -152+122
53
Over / Under
- - -145+116
53.5
Over / Under
- - -139+110
54
Over / Under
- - -128+104
54.5
Over / Under
- -115-105 -115-105
55
Over / Under
- - -112-108
55.5
Over / Under
- - -106-114
56
Over / Under
- - -102-118
56.5
Over / Under
- - +101-122
57
Over / Under
- - +108-135
57.5
Over / Under
- - +116-145
58
Over / Under
- - +125-154
58.5
Over / Under
- - +134-164
59
Over / Under
- - +140-175
59.5
Over / Under
- - +145-179
60
Over / Under
- - +152-189
60.5
Over / Under
- - +158-196
61
Over / Under
- - +168-222
61.5
Over / Under
- - +174-233
62
Over / Under
- - +180-250
62.5
Over / Under
- - +186-263
63
Over / Under
- - +205-278
63.5
Over / Under
- - +210-286
64
Over / Under
- - +230-312
64.5
Over / Under
- - +238-323
65
Over / Under
- - +260-370
65.5
Over / Under
- - +268-385
66
Over / Under
- - +278-417
66.5
Over / Under
- - +282-417
67
Over / Under
- - +314-455
67.5
Over / Under
- - +320-476
68
Over / Under
- - +336-526
68.5
Over / Under
- - +340-556
69
Over / Under
- - +360-625

Top number: over; bottom: under. Gold = best top number.